紀要論文

細胞外電位計測によるニワトリ胚由来心臓組織片同士の拍動同期メカニズム解析

ANALYSIS OF BEAT SYNCHRONIZATION MECHANISM IN EMBRYONIC CHICK CARDIAC TISSUE PIECES BY FIELD POTENTIAL MEASUREMENT.

jpn

21879923

https://doi.org/10.15002/00021624

法政大学大学院理工学研究科

法政大学大学院紀要. 理工学・工学研究科編

59

1

2

2018-03-31

Version of Record

ヘッダー部分に誤記 ; (誤) 法政大学大学院理工学・工学研究科紀要 (正) 法政大学大学院紀要. 理工学・工学研究科編

In cardiac regenerative medicine, synchronization between artificial cardiac tissue sheet and original cardiac tissue is important. However, synchronization process is unclear. Therefore, the synchronization process between chick embryo-derived cardiac tissue pieces was investigated. In the heart, there are various parts such as the ventricle, the atrium, the sinoatrial node, etc., and the process of synchronization may be different at each parts. Two cardiac tissue pieces were placed on the Multi Electrode Array (MEA) and the synchronization process of the ventricular pair, the atrial pair or the ventricle and the atrial pair was compared. In conclusion, the synchronization process was different between the ventricular pair and the atrial pair. In addition, the ventricular and the atrial pair did not synchronize completely. Further elucidation of the beating synchronization mechanism between cardiac tissue pieces might be useful in cardiac regenerative medicine.

Article

AA12677220